Perfection of Wound Healing to the Rescue of Patients Struggling Against Fatal Diseases Evolving Due to Wound Unhealing

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Ming C. Liau , Christine L. Craig , Linda L. Baker

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Published: 4 February 2026 | Article Type : Research Article

Abstract

The object of this article is to correct the mistakes of health authorities on fatal diseases evolving due to wound unhealing. Health profession is an authoritarian profession. Policies are made by the top authorities for the profession to follow. Intelligent authorities can make good policies to enhance the reputation of health profession and to benefit patients. But inept authorities can make bad policies to damage the reputation of health profession and to hurt patients. Cancer and cardiovascular diseases (CVDs) are the top killers of humans for a very long time. Authorities in charge of cancer and cardiovascular diseases are apparently incompetent to let these diseases to become top killers for so long.
Cancer is a disease evolving due to wound unhealing, which was a valid concept of cancer introduced by Virchow in 1858. We unknowingly pursued cancer therapy following the guidance of Virchow to discover abnormal methylation enzymes (MEs), chemo-surveillance and the mechanism of wound healing to support the valid concept of cancer evolving due to wound unhealing. Obviously, perfection of wound healing is the only option for the solution of cancer correctly. Cancer authorities directed cancer therapies in opposition to the advice of Virchow by the employment of toxic agents to create wounds, thus, stirring up cancer as a giant killer. Cancer authorities are supposed to save cancer patients. But they function as the killers of advanced cancer patients instead. Cancer therapies based on the killing of cancer cells (CCs) can only benefit a small minority of cancer patients in the early stage. The survival of early stage cancer patients also critically depends on the restoration of chemo-surveillance to subdue surviving cancer stem cells (CSCs).
CVDs are also evolved due to wound unhealing. The damage to the inner lining of artery triggers the buildup of progenitor stem cells (PSCs) to heal the wound. Inability of PSCs to undergo terminal differentiation (TD) to heal the wound triggers the secondary responses of leukocyte infiltration and the deposit of light density lipoprotein to display the symptom of hypertension. CVDs authorities employ medications to reduce hypertension, which are not very effective to result in CVDs as the top killer of humans. Perfection of wound healing to remove the primary cause of wound unhealing is a more effective approach to the solution of CVDs.
Wound unhealing is the primary cause of fatal diseases such as the white lung of COVID-19 infection, liver cirrhosis, dementia and organ failures. Perfection of wound healing is the best approach for the solution of fatal diseases evolving due to wound unhealing.

Keywords: Cancer, CVDs, Health Profession, Wound Healing.

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Ming C. Liau , Christine L. Craig , Linda L. Baker. (2026-02-04). "Perfection of Wound Healing to the Rescue of Patients Struggling Against Fatal Diseases Evolving Due to Wound Unhealing." *Volume 6*, 1, 1-12